Next, take the necessary steps to remove malware from your device. The first thing you should do is check chrome://extensions for any extensions you don't remember installing yourself. Malware often looks for and uninstalls extensions that can keep them from doing their nefarious work. If AdBlock is constantly being uninstalled or disabled every time you open Chrome, it could mean your computer is infected with malware. Either way, it could be an issue with malware, an extension that doesn't like AdBlock, a broken installation of AdBlock, or even Chrome itself. Has the AdBlock button vanished from the browser toolbar every time you open Chrome? Visit chrome://extensions and see whether AdBlock has been disabled or even uninstalled.